BindingDB PrimarySearch

BDBM50064252 (2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid::CHEMBL44582

SMILES: CCC1=C(C(C)C)\C(CCC1)=C\C(\C)=C\C=C\C(\C)=C/C(O)=O

InChI Key: InChIKey=OZUIXDDSOLQKNK-KTBBHIKBSA-N

Data: 4 IC50 4 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50064252
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor beta (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	371	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid A receptor RAR beta				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor alpha (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gamma				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid A receptor RAR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid A receptor RAR gamma				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR beta				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor alpha (Mus musculus)	BDBM50064252 ((2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid X receptor RXR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair