BindingDB PrimarySearch

BDBM50064253 (2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid::CHEMBL44979

SMILES: C\C(\C=C/C=C(/C)\C=C1/CCCc2ccccc12)=C/C(O)=O

InChI Key: InChIKey=PPGNMFUMZSAZCW-BVTSRZRCSA-N

Data: 4 IC50 4 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50064253
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor beta (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid A receptor RAR beta				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor alpha (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	118	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor alpha (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid X receptor RXR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR beta				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid A receptor RAR alpha				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Inhibition of binding to retinoid A receptor RAR gamma				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma (Mus musculus)	BDBM50064253 ((2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gamma				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair