BDBM50066023 CHEMBL3401474

SMILES: Cc1cc2c(nc(CCCCCN3CCN(Cc4ccccc4)CC3)[nH]c2=O)s1

InChI Key: InChIKey=RSFCFVOFSOMVAL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50066023 (CHEMBL3401474) Show SMILES Cc1cc2c(nc(CCCCCN3CCN(Cc4ccccc4)CC3)[nH]c2=O)s1 Show InChI InChI=1S/C23H30N4OS/c1-18-16-20-22(28)24-21(25-23(20)29-18)10-6-3-7-11-26-12-14-27(15-13-26)17-19-8-4-2-5-9-19/h2,4-5,8-9,16H,3,6-7,10-15,17H2,1H3,(H,24,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	147	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT7 receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 25: 1427-30 (2015) Article DOI: 10.1016/j.bmcl.2015.02.042 BindingDB Entry DOI: 10.7270/Q23R0VJN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50066023 (CHEMBL3401474) Show SMILES Cc1cc2c(nc(CCCCCN3CCN(Cc4ccccc4)CC3)[nH]c2=O)s1 Show InChI InChI=1S/C23H30N4OS/c1-18-16-20-22(28)24-21(25-23(20)29-18)10-6-3-7-11-26-12-14-27(15-13-26)17-19-8-4-2-5-9-19/h2,4-5,8-9,16H,3,6-7,10-15,17H2,1H3,(H,24,25,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	363	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT from human 5-HT1A receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 25: 1427-30 (2015) Article DOI: 10.1016/j.bmcl.2015.02.042 BindingDB Entry DOI: 10.7270/Q23R0VJN
					More data for this Ligand-Target Pair