BDBM50066024 CHEMBL3401475

SMILES: Cc1sc2nc(CCCCCN3CCC(Cc4ccccc4)CC3)[nH]c(=O)c2c1C

InChI Key: InChIKey=SGQOVLUMNHAQHS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50066024 (CHEMBL3401475) Show SMILES Cc1sc2nc(CCCCCN3CCC(Cc4ccccc4)CC3)[nH]c(=O)c2c1C Show InChI InChI=1S/C25H33N3OS/c1-18-19(2)30-25-23(18)24(29)26-22(27-25)11-7-4-8-14-28-15-12-21(13-16-28)17-20-9-5-3-6-10-20/h3,5-6,9-10,21H,4,7-8,11-17H2,1-2H3,(H,26,27,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT from human 5-HT1A receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 25: 1427-30 (2015) Article DOI: 10.1016/j.bmcl.2015.02.042 BindingDB Entry DOI: 10.7270/Q23R0VJN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50066024 (CHEMBL3401475) Show SMILES Cc1sc2nc(CCCCCN3CCC(Cc4ccccc4)CC3)[nH]c(=O)c2c1C Show InChI InChI=1S/C25H33N3OS/c1-18-19(2)30-25-23(18)24(29)26-22(27-25)11-7-4-8-14-28-15-12-21(13-16-28)17-20-9-5-3-6-10-20/h3,5-6,9-10,21H,4,7-8,11-17H2,1-2H3,(H,26,27,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT7 receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 25: 1427-30 (2015) Article DOI: 10.1016/j.bmcl.2015.02.042 BindingDB Entry DOI: 10.7270/Q23R0VJN
					More data for this Ligand-Target Pair