BDBM50066090 CHEMBL3402937
SMILES: NC(=O)c1cc(sc1NC(=S)Nc1ccc(Br)cc1)-c1ccccc1
InChI Key: InChIKey=GCKSQUBUSOLFCI-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA gyrase subunit B (Mycobacterium smegmatis) | BDBM50066090 (CHEMBL3402937) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP... | Bioorg Med Chem 23: 1402-12 (2015) Article DOI: 10.1016/j.bmc.2015.02.032 BindingDB Entry DOI: 10.7270/Q2QF8VKM | |||||||||||
More data for this Ligand-Target Pair |