BDBM50066422 CHEMBL326130::N,N'-Bis-biphenyl-4-yl-guanidine

SMILES: NC(Nc1ccc(cc1)-c1ccccc1)=Nc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=LAZZQYZMHUJGST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type II alpha subunit (Rattus norvegicus)	BDBM50066422 (CHEMBL326130 | N,N'-Bis-biphenyl-4-yl-guanidine) Show SMILES NC(Nc1ccc(cc1)-c1ccccc1)=Nc1ccc(cc1)-c1ccccc1 |w:15.17| Show InChI InChI=1S/C25H21N3/c26-25(27-23-15-11-21(12-16-23)19-7-3-1-4-8-19)28-24-17-13-22(14-18-24)20-9-5-2-6-10-20/h1-18H,(H3,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair