BDBM50066424 CHEMBL331126::N,N'-Bis-(4-phenylsulfanyl-phenyl)-guanidine

SMILES: NC(Nc1ccc(Sc2ccccc2)cc1)=Nc1ccc(Sc2ccccc2)cc1

InChI Key: InChIKey=LJWSGBDUJMBMKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type II alpha subunit (Rattus norvegicus)	BDBM50066424 (CHEMBL331126 | N,N'-Bis-(4-phenylsulfanyl-phenyl)-...) Show SMILES NC(Nc1ccc(Sc2ccccc2)cc1)=Nc1ccc(Sc2ccccc2)cc1 |w:16.18| Show InChI InChI=1S/C25H21N3S2/c26-25(27-19-11-15-23(16-12-19)29-21-7-3-1-4-8-21)28-20-13-17-24(18-14-20)30-22-9-5-2-6-10-22/h1-18H,(H3,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair