BDBM50066738 CHEMBL3403118

SMILES: Nc1cnc2sc(c(-c3cccc(Cl)c3)c2c1)S(=O)(=O)c1cccc(c1)C#N

InChI Key: InChIKey=HTMGCCBNHBIGON-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50066738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50066738 (CHEMBL3403118) Show SMILES Nc1cnc2sc(c(-c3cccc(Cl)c3)c2c1)S(=O)(=O)c1cccc(c1)C#N Show InChI InChI=1S/C20H12ClN3O2S2/c21-14-5-2-4-13(8-14)18-17-9-15(23)11-24-19(17)27-20(18)28(25,26)16-6-1-3-12(7-16)10-22/h1-9,11H,23H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptor				Bioorg Med Chem Lett 25: 1724-9 (2015) Article DOI: 10.1016/j.bmcl.2015.02.073 BindingDB Entry DOI: 10.7270/Q2JS9S47
					More data for this Ligand-Target Pair