BDBM50067107 CHEMBL424259::N-(2-Pyridin-2-yl-quinazolin-4-yl)-benzamide

SMILES: O=C(Nc1nc(nc2ccccc12)-c1ccccn1)c1ccccc1

InChI Key: InChIKey=JQMAQOJNNLVOTP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50067107 (CHEMBL424259 | N-(2-Pyridin-2-yl-quinazolin-4-yl)-...) Show SMILES O=C(Nc1nc(nc2ccccc12)-c1ccccn1)c1ccccc1 Show InChI InChI=1S/C20H14N4O/c25-20(14-8-2-1-3-9-14)24-18-15-10-4-5-11-16(15)22-19(23-18)17-12-6-7-13-21-17/h1-13H,(H,22,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cells				J Med Chem 44: 749-62 (2001) BindingDB Entry DOI: 10.7270/Q2H132Q0
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50067107 (CHEMBL424259 | N-(2-Pyridin-2-yl-quinazolin-4-yl)-...) Show SMILES O=C(Nc1nc(nc2ccccc12)-c1ccccn1)c1ccccc1 Show InChI InChI=1S/C20H14N4O/c25-20(14-8-2-1-3-9-14)24-18-15-10-4-5-11-16(15)22-19(23-18)17-12-6-7-13-21-17/h1-13H,(H,22,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Tested for antagonist activity by displacement of specific [125I]-AB-MECA binding at human Adenosine A3 receptor expressed in HEK 293 cells.				J Med Chem 41: 3994-4000 (1998) Article DOI: 10.1021/jm980037i BindingDB Entry DOI: 10.7270/Q2891513
					More data for this Ligand-Target Pair