BDBM50067338 CHEMBL3401773

SMILES: Cc1nc(Nc2ccc(O)cc2)c2cc(sc2n1)-c1ccccc1

InChI Key: InChIKey=KNNGYNBPDGYIKK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50067338 (CHEMBL3401773) Show SMILES Cc1nc(Nc2ccc(O)cc2)c2cc(sc2n1)-c1ccccc1 Show InChI InChI=1S/C19H15N3OS/c1-12-20-18(22-14-7-9-15(23)10-8-14)16-11-17(24-19(16)21-12)13-5-3-2-4-6-13/h2-11,23H,1H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Biology and Genetics NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...				Bioorg Med Chem 23: 2287-93 (2015) Article DOI: 10.1016/j.bmc.2014.12.044 BindingDB Entry DOI: 10.7270/Q2RB7692
					More data for this Ligand-Target Pair