BDBM50067825 3-[(R)-3-(1,5-Dimethyl-hexyl)-3a-methyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-yl]-propionic acid::CHEMBL334930

SMILES: CC(C)CCCC(C)C1CCC2C3CCC(=O)C(CCC(O)=O)C3CC[C@]12C

InChI Key: InChIKey=NHMHIJGSSVRXTO-QLKOWSNDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50067825 (3-[(R)-3-(1,5-Dimethyl-hexyl)-3a-methyl-7-oxo-dode...) Show SMILES CC(C)CCCC(C)C1CCC2C3CCC(=O)C(CCC(O)=O)C3CC[C@]12C Show InChI InChI=1S/C25H42O3/c1-16(2)6-5-7-17(3)21-10-11-22-19-8-12-23(26)20(9-13-24(27)28)18(19)14-15-25(21,22)4/h16-22H,5-15H2,1-4H3,(H,27,28)/t17?,18?,19?,20?,21?,22?,25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human Farnesyltransferase				J Med Chem 41: 4492-501 (1998) Article DOI: 10.1021/jm980356+ BindingDB Entry DOI: 10.7270/Q23779DQ
					More data for this Ligand-Target Pair