BDBM50067830 (3aR,6R,7R)-6-(2-Carboxy-ethyl)-3-(1,5-dimethyl-hexyl)-3a,6-dimethyl-dodecahydro-cyclopenta[a]naphthalene-7-carboxylic acid::CHEMBL139844

SMILES: CC(C)CCCC(C)C1CCC2C3CC[C@@H](C(O)=O)[C@](C)(CCC(O)=O)C3CC[C@]12C

InChI Key: InChIKey=CUKZMECJGGZUMT-CSBIMFKGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50067830 ((3aR,6R,7R)-6-(2-Carboxy-ethyl)-3-(1,5-dimethyl-he...) Show SMILES CC(C)CCCC(C)C1CCC2C3CC[C@@H](C(O)=O)[C@](C)(CCC(O)=O)C3CC[C@]12C Show InChI InChI=1S/C27H46O4/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23(25(30)31)27(5,16-14-24(28)29)22(19)13-15-26(20,21)4/h17-23H,6-16H2,1-5H3,(H,28,29)(H,30,31)/t18?,19?,20?,21?,22?,23-,26+,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human Farnesyltransferase				J Med Chem 41: 4492-501 (1998) Article DOI: 10.1021/jm980356+ BindingDB Entry DOI: 10.7270/Q23779DQ
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