BDBM50067843 (S)-2-[(3aR,6R)-3-(1,5-Dimethyl-hexyl)-3a,6-dimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-ylmethyl]-succinic acid::2-[3-(1,5-Dimethyl-hexyl)-3a,6-dimethyl-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-ylmethyl]-succinic acid(Des-B)::CHEMBL35674

SMILES: CC(C)CCCC(C)C1CCC2C3CCC(=O)[C@](C)(C[C@@H](CC(O)=O)C(O)=O)C3CC[C@]12C

InChI Key: InChIKey=DSMMOUACIAORLU-QNVPDBANSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067843   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50067843 ((S)-2-[(3aR,6R)-3-(1,5-Dimethyl-hexyl)-3a,6-dimeth...) Show SMILES CC(C)CCCC(C)C1CCC2C3CCC(=O)[C@](C)(C[C@@H](CC(O)=O)C(O)=O)C3CC[C@]12C Show InChI InChI=1S/C28H46O5/c1-17(2)7-6-8-18(3)21-10-11-22-20-9-12-24(29)28(5,23(20)13-14-27(21,22)4)16-19(26(32)33)15-25(30)31/h17-23H,6-16H2,1-5H3,(H,30,31)(H,32,33)/t18?,19-,20?,21?,22?,23?,27-,28-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Milan Curated by ChEMBL					Assay Description Inhibition of Farnesyltransferase				J Med Chem 45: 1460-5 (2002) BindingDB Entry DOI: 10.7270/Q2RV0PDQ
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50067843 ((S)-2-[(3aR,6R)-3-(1,5-Dimethyl-hexyl)-3a,6-dimeth...) Show SMILES CC(C)CCCC(C)C1CCC2C3CCC(=O)[C@](C)(C[C@@H](CC(O)=O)C(O)=O)C3CC[C@]12C Show InChI InChI=1S/C28H46O5/c1-17(2)7-6-8-18(3)21-10-11-22-20-9-12-24(29)28(5,23(20)13-14-27(21,22)4)16-19(26(32)33)15-25(30)31/h17-23H,6-16H2,1-5H3,(H,30,31)(H,32,33)/t18?,19-,20?,21?,22?,23?,27-,28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Farnesyltransferase				J Med Chem 41: 4492-501 (1998) Article DOI: 10.1021/jm980356+ BindingDB Entry DOI: 10.7270/Q23779DQ
					More data for this Ligand-Target Pair