null

SMILES: C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F

InChI Key: InChIKey=CMHJMUZTXMDMKL-SJLPKXTDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50069059 ((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...) Show SMILES C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F Show InChI InChI=1S/C19H21F3N2O/c1-17(2)5-4-6-18(3)12-7-10-11(19(20,21)22)8-15(25)23-13(10)9-14(12)24-16(17)18/h7-9,16,24H,4-6H2,1-3H3,(H,23,25)/t16-,18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against Androgen receptor transfected into COS cells				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50069059 ((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...) Show SMILES C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F Show InChI InChI=1S/C19H21F3N2O/c1-17(2)5-4-6-18(3)12-7-10-11(19(20,21)22)8-15(25)23-13(10)9-14(12)24-16(17)18/h7-9,16,24H,4-6H2,1-3H3,(H,23,25)/t16-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Agonistic activity (EC50) against human androgen receptor (hAR) in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50069059 ((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...) Show SMILES C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F Show InChI InChI=1S/C19H21F3N2O/c1-17(2)5-4-6-18(3)12-7-10-11(19(20,21)22)8-15(25)23-13(10)9-14(12)24-16(17)18/h7-9,16,24H,4-6H2,1-3H3,(H,23,25)/t16-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against Glucocorticoid receptor in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50069059 ((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...) Show SMILES C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F Show InChI InChI=1S/C19H21F3N2O/c1-17(2)5-4-6-18(3)12-7-10-11(19(20,21)22)8-15(25)23-13(10)9-14(12)24-16(17)18/h7-9,16,24H,4-6H2,1-3H3,(H,23,25)/t16-,18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Agonistic activity (EC50) against human androgen receptor (hAR) in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50069059 ((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...) Show SMILES C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F Show InChI InChI=1S/C19H21F3N2O/c1-17(2)5-4-6-18(3)12-7-10-11(19(20,21)22)8-15(25)23-13(10)9-14(12)24-16(17)18/h7-9,16,24H,4-6H2,1-3H3,(H,23,25)/t16-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against hPR in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50069059 ((5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,...) Show SMILES C[C@]12CCCC(C)(C)[C@H]1Nc1cc3[nH]c(=O)cc(c3cc21)C(F)(F)F Show InChI InChI=1S/C19H21F3N2O/c1-17(2)5-4-6-18(3)12-7-10-11(19(20,21)22)8-15(25)23-13(10)9-14(12)24-16(17)18/h7-9,16,24H,4-6H2,1-3H3,(H,23,25)/t16-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity against hMR in cotransfected CV-1 cell				Bioorg Med Chem Lett 8: 745-50 (1999) BindingDB Entry DOI: 10.7270/Q2XS5THG
					More data for this Ligand-Target Pair