BDBM50069371 (1-{(R)-1-{3-[(E)-2-(8,8-Dimethyl-5,6,7,8-tetrahydro-quinolin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::CHEMBL348229

SMILES: CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCC(C)(C)c3n2)c1

InChI Key: InChIKey=IBDAOFPNZMUFAK-CGNAPUSOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50069371 ((1-{(R)-1-{3-[(E)-2-(8,8-Dimethyl-5,6,7,8-tetrahyd...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCC(C)(C)c3n2)c1 Show InChI InChI=1S/C37H45NO3S/c1-35(2)20-8-12-28-15-18-30(38-34(28)35)17-14-26-9-7-11-29(23-26)32(42-25-37(21-22-37)24-33(39)40)19-16-27-10-5-6-13-31(27)36(3,4)41/h5-7,9-11,13-15,17-18,23,32,41H,8,12,16,19-22,24-25H2,1-4H3,(H,39,40)/b17-14+/t32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50069371 ((1-{(R)-1-{3-[(E)-2-(8,8-Dimethyl-5,6,7,8-tetrahyd...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCC(C)(C)c3n2)c1 Show InChI InChI=1S/C37H45NO3S/c1-35(2)20-8-12-28-15-18-30(38-34(28)35)17-14-26-9-7-11-29(23-26)32(42-25-37(21-22-37)24-33(39)40)19-16-27-10-5-6-13-31(27)36(3,4)41/h5-7,9-11,13-15,17-18,23,32,41H,8,12,16,19-22,24-25H2,1-4H3,(H,39,40)/b17-14+/t32-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50069371 ((1-{(R)-1-{3-[(E)-2-(8,8-Dimethyl-5,6,7,8-tetrahyd...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCC(C)(C)c3n2)c1 Show InChI InChI=1S/C37H45NO3S/c1-35(2)20-8-12-28-15-18-30(38-34(28)35)17-14-26-9-7-11-29(23-26)32(42-25-37(21-22-37)24-33(39)40)19-16-27-10-5-6-13-31(27)36(3,4)41/h5-7,9-11,13-15,17-18,23,32,41H,8,12,16,19-22,24-25H2,1-4H3,(H,39,40)/b17-14+/t32-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair