BDBM50070050 2-((4aR,10bR)-4,10b-Dimethyl-3-oxo-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-8-yl)-N,N-diethyl-acetamide::CHEMBL129130

SMILES: CCN(CC)C(=O)Cc1ccc2c(CC[C@H]3N(C)C(=O)CC[C@]23C)c1

InChI Key: InChIKey=WDCTUQIXUQBBEI-WIYYLYMNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 5-alpha-reductase (Homo sapiens (Human))	BDBM50070050 (2-((4aR,10bR)-4,10b-Dimethyl-3-oxo-1,2,3,4,4a,5,6,...) Show SMILES CCN(CC)C(=O)Cc1ccc2c(CC[C@H]3N(C)C(=O)CC[C@]23C)c1 Show InChI InChI=1S/C21H30N2O2/c1-5-23(6-2)20(25)14-15-7-9-17-16(13-15)8-10-18-21(17,3)12-11-19(24)22(18)4/h7,9,13,18H,5-6,8,10-12,14H2,1-4H3/t18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase type 2 as [3H]-T to [3H]-DHT conversion human prostate nuclear membrane				Bioorg Med Chem Lett 8: 395-8 (1999) BindingDB Entry DOI: 10.7270/Q2CN732C
					More data for this Ligand-Target Pair
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50070050 (2-((4aR,10bR)-4,10b-Dimethyl-3-oxo-1,2,3,4,4a,5,6,...) Show SMILES CCN(CC)C(=O)Cc1ccc2c(CC[C@H]3N(C)C(=O)CC[C@]23C)c1 Show InChI InChI=1S/C21H30N2O2/c1-5-23(6-2)20(25)14-15-7-9-17-16(13-15)8-10-18-21(17,3)12-11-19(24)22(18)4/h7,9,13,18H,5-6,8,10-12,14H2,1-4H3/t18-,21-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase type 1 enzyme based on the conversion of [3H]-T to [3H]-DHT in nuclear membrane preparations fr...				Bioorg Med Chem Lett 8: 395-8 (1999) BindingDB Entry DOI: 10.7270/Q2CN732C
					More data for this Ligand-Target Pair