BDBM50070067 CHEMBL3407807

SMILES: Cl.Fc1cccc(CCNCc2ccnc(n2)-n2ccnc2)c1

InChI Key: InChIKey=OLSARYFCSFFWNW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric-oxide synthase, brain (Rattus norvegicus (rat))	BDBM50070067 (CHEMBL3407807) Show SMILES Cl.Fc1cccc(CCNCc2ccnc(n2)-n2ccnc2)c1 Show InChI InChI=1S/C16H16FN5.ClH/c17-14-3-1-2-13(10-14)4-6-18-11-15-5-7-20-16(21-15)22-9-8-19-12-22;/h1-3,5,7-10,12,18H,4,6,11H2;1H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Binding affinity to recombinant rat neuronal NOS overexpressed in Escherichia coli assessed as production of nitric oxide from L-arginine measured fo...				J Med Chem 58: 1067-88 (2015) Article DOI: 10.1021/jm501719e BindingDB Entry DOI: 10.7270/Q2CR5W25
					More data for this Ligand-Target Pair