BDBM50070104 (2E)-3-(3-Hydroxy-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::(E)-3-(3''-Hydroxy-4''-methoxyphenyl)-1-(3',4',5'-trimethoxyphenyl)prop-2-en-1-one::(E)-3-(3''-hydroxy-4''-methoxyphenyl)-1-(3',4',5'-trimethoxyphenyl)-2-propen-1-one::(E)-3-(3-Hydroxy-4-methoxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone::(E)-3-(3-hydroxy-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::3-(3-hydroxy-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::3-hydroxy-3',4,4',5'-tetramethoxychalcone::CHEMBL9941

SMILES: COc1ccc(\C=C\C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key: InChIKey=IKMOZUDCUBMIRL-FNORWQNLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50070104 ((2E)-3-(3-Hydroxy-4-methoxyphenyl)-1-(3,4,5-trimet...) Show SMILES COc1ccc(\C=C\C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C19H20O6/c1-22-16-8-6-12(9-15(16)21)5-7-14(20)13-10-17(23-2)19(25-4)18(11-13)24-3/h5-11,21H,1-4H3/b7-5+	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Calabria Curated by ChEMBL					Assay Description Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysis				Bioorg Med Chem Lett 20: 1990-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.113 BindingDB Entry DOI: 10.7270/Q2G73DW4
					More data for this Ligand-Target Pair
Tubulin beta-1 chain (Homo sapiens (Human))	BDBM50070104 ((2E)-3-(3-Hydroxy-4-methoxyphenyl)-1-(3,4,5-trimet...) Show SMILES COc1ccc(\C=C\C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C19H20O6/c1-22-16-8-6-12(9-15(16)21)5-7-14(20)13-10-17(23-2)19(25-4)18(11-13)24-3/h5-11,21H,1-4H3/b7-5+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
University of Salford Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of tubulin polymerization				J Med Chem 48: 457-65 (2005) Article DOI: 10.1021/jm049444m BindingDB Entry DOI: 10.7270/Q2416WKV
					More data for this Ligand-Target Pair