BDBM50071896 4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl)-1H-pyrrol-3-yl]-2-methyl-pyridine::CHEMBL91934

SMILES: Cc1cc(ccn1)-c1cc([nH]c1-c1ccc(F)cc1)-c1ccc(cc1)S(C)=O

InChI Key: InChIKey=LFVBYBOZGWMFLQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase p38 alpha (Rattus norvegicus)	BDBM50071896 (4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...) Show SMILES Cc1cc(ccn1)-c1cc([nH]c1-c1ccc(F)cc1)-c1ccc(cc1)S(C)=O Show InChI InChI=1S/C23H19FN2OS/c1-15-13-18(11-12-25-15)21-14-22(16-5-9-20(10-6-16)28(2)27)26-23(21)17-3-7-19(24)8-4-17/h3-14,26H,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibitory potency evaluated against rat p38 kinase				Bioorg Med Chem Lett 8: 2689-94 (1999) BindingDB Entry DOI: 10.7270/Q27D2T9N
					More data for this Ligand-Target Pair