BDBM50071907 2-(4-Chloro-phenyl)-4-(4-fluoro-phenyl)-5-pyridin-4-yl-1,2-dihydro-pyrazol-3-one::CHEMBL91730

SMILES: Fc1ccc(cc1)-c1c([nH]n(-c2ccc(Cl)cc2)c1=O)-c1ccncc1

InChI Key: InChIKey=DZFBYHUKZSRPHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase p38 alpha (Rattus norvegicus)	BDBM50071907 (2-(4-Chloro-phenyl)-4-(4-fluoro-phenyl)-5-pyridin-...) Show SMILES Fc1ccc(cc1)-c1c([nH]n(-c2ccc(Cl)cc2)c1=O)-c1ccncc1 Show InChI InChI=1S/C20H13ClFN3O/c21-15-3-7-17(8-4-15)25-20(26)18(13-1-5-16(22)6-2-13)19(24-25)14-9-11-23-12-10-14/h1-12,24H	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibitory potency evaluated against rat p38 kinase				Bioorg Med Chem Lett 8: 2689-94 (1999) BindingDB Entry DOI: 10.7270/Q27D2T9N
					More data for this Ligand-Target Pair