BDBM50072191 1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one::1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one::CHEMBL96006

SMILES: O=C1CCN2C(CCc3ccccc23)=C1

InChI Key: InChIKey=OPJKPSOLCGGXEW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50072191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50072191 (1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one | 1...) Show SMILES O=C1CCN2C(CCc3ccccc23)=C1 |c:15| Show InChI InChI=1S/C13H13NO/c15-12-7-8-14-11(9-12)6-5-10-3-1-2-4-13(10)14/h1-4,9H,5-8H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Inhibition of human Steroid 5-alpha-reductase type I				Bioorg Med Chem Lett 10: 353-6 (2000) BindingDB Entry DOI: 10.7270/Q2K35SVJ
					More data for this Ligand-Target Pair
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50072191 (1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one | 1...) Show SMILES O=C1CCN2C(CCc3ccccc23)=C1 |c:15| Show InChI InChI=1S/C13H13NO/c15-12-7-8-14-11(9-12)6-5-10-3-1-2-4-13(10)14/h1-4,9H,5-8H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50072191 (1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one | 1...) Show SMILES O=C1CCN2C(CCc3ccccc23)=C1 |c:15| Show InChI InChI=1S/C13H13NO/c15-12-7-8-14-11(9-12)6-5-10-3-1-2-4-13(10)14/h1-4,9H,5-8H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human Steroid 5-alpha-reductase type 1 from recombinant CHO cells				Bioorg Med Chem Lett 8: 2871-6 (1999) BindingDB Entry DOI: 10.7270/Q2CC1169
					More data for this Ligand-Target Pair
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50072191 (1,2,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one | 1...) Show SMILES O=C1CCN2C(CCc3ccccc23)=C1 |c:15| Show InChI InChI=1S/C13H13NO/c15-12-7-8-14-11(9-12)6-5-10-3-1-2-4-13(10)14/h1-4,9H,5-8H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...				J Med Chem 47: 3546-60 (2004) Article DOI: 10.1021/jm031131o BindingDB Entry DOI: 10.7270/Q24J0DKZ
					More data for this Ligand-Target Pair