BDBM50072243 4-(3,4-Dichloro-phenyl)-4-oxo-2-phenyl-butyric acid::CHEMBL99338

SMILES: OC(=O)C(CC(=O)c1ccc(Cl)c(Cl)c1)c1ccccc1

InChI Key: InChIKey=UKUPGIQPUKVYDP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50072243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine 3-monooxygenase (Rattus norvegicus)	BDBM50072243 (4-(3,4-Dichloro-phenyl)-4-oxo-2-phenyl-butyric aci...) Show SMILES OC(=O)C(CC(=O)c1ccc(Cl)c(Cl)c1)c1ccccc1 Show InChI InChI=1S/C16H12Cl2O3/c17-13-7-6-11(8-14(13)18)15(19)9-12(16(20)21)10-4-2-1-3-5-10/h1-8,12H,9H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia& Upjohn Curated by ChEMBL					Assay Description Inhibition of rat liver KYN 3-OHase.				Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K
					More data for this Ligand-Target Pair