BDBM50072291 4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan-3-ylmethyl)-benzamidine; compound with acetic acid::CHEMBL323544
SMILES: NC(=N)c1ccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)cc1
InChI Key: InChIKey=POQJVFNWHVBUIE-UPJWGTAASA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prothrombin (Homo sapiens (Human)) | BDBM50072291![]() (4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development Curated by ChEMBL | Assay Description Inhibition of thrombin | Bioorg Med Chem Lett 8: 2955-60 (1999) Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-1 (Homo sapiens (Human)) | BDBM50072291![]() (4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development Curated by ChEMBL | Assay Description Inhibition of trypsin | Bioorg Med Chem Lett 8: 2955-60 (1999) Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymotrypsin (Homo sapiens (Human)) | BDBM50072291![]() (4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen | Bioorg Med Chem Lett 8: 2955-60 (1999) Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F | |||||||||||
More data for this Ligand-Target Pair |