null

SMILES: OC(=O)C[C@@H]1Nc2ccc(cc2CN(CC(O)=O)C1=O)C(=O)NCc1nc2ccccc2[nH]1

InChI Key: InChIKey=WNDWXDWEAFPJDS-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50072499 (CHEMBL322783 | {(S)-7-[(1H-Benzoimidazol-2-ylmethy...) Show SMILES OC(=O)C[C@@H]1Nc2ccc(cc2CN(CC(O)=O)C1=O)C(=O)NCc1nc2ccccc2[nH]1 Show InChI InChI=1S/C22H21N5O6/c28-19(29)8-17-22(33)27(11-20(30)31)10-13-7-12(5-6-14(13)24-17)21(32)23-9-18-25-15-3-1-2-4-16(15)26-18/h1-7,17,24H,8-11H2,(H,23,32)(H,25,26)(H,28,29)(H,30,31)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity evaluated against vitronectin receptor (alphaV-beta3) receptor				Bioorg Med Chem Lett 8: 3165-70 (1999) BindingDB Entry DOI: 10.7270/Q2NG4PSF
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50072499 (CHEMBL322783 | {(S)-7-[(1H-Benzoimidazol-2-ylmethy...) Show SMILES OC(=O)C[C@@H]1Nc2ccc(cc2CN(CC(O)=O)C1=O)C(=O)NCc1nc2ccccc2[nH]1 Show InChI InChI=1S/C22H21N5O6/c28-19(29)8-17-22(33)27(11-20(30)31)10-13-7-12(5-6-14(13)24-17)21(32)23-9-18-25-15-3-1-2-4-16(15)26-18/h1-7,17,24H,8-11H2,(H,23,32)(H,25,26)(H,28,29)(H,30,31)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated plates				Bioorg Med Chem Lett 8: 3165-70 (1999) BindingDB Entry DOI: 10.7270/Q2NG4PSF
					More data for this Ligand-Target Pair