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SMILES: OC(=O)c1cc(OC(=O)\C=C\c2ccc(O)c(O)c2)cc(OC(=O)\C=C\c2ccc(O)c(O)c2)c1

InChI Key: InChIKey=SXLGXPZQECDQIF-FCXRPNKRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073637   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50073637
PNG
(3,5-Bis-[(E)-3-(3,4-dihydroxy-phenyl)-acryloyloxy]...)
Show SMILES OC(=O)c1cc(OC(=O)\C=C\c2ccc(O)c(O)c2)cc(OC(=O)\C=C\c2ccc(O)c(O)c2)c1
Show InChI InChI=1S/C25H18O10/c26-19-5-1-14(9-21(19)28)3-7-23(30)34-17-11-16(25(32)33)12-18(13-17)35-24(31)8-4-15-2-6-20(27)22(29)10-15/h1-13,26-29H,(H,32,33)/b7-3+,8-4+
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.90E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity against Human Immunodeficiency Virus Type 1 integrase (HIV-1 IN) in the disintegration assay.

J Med Chem 42: 497-509 (1999)


Article DOI: 10.1021/jm9804735
BindingDB Entry DOI: 10.7270/Q2G161J5
More data for this
Ligand-Target Pair