Found 9 hits for monomerid = 50073691 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
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Similars
| Article PubMed
| 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor |
J Med Chem 42: 526-31 (1999)
Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM |
More data for this Ligand-Target Pair | |
Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
(RAT) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
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| Article PubMed
| 33.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by PDSP Ki Database
| |
Neuropharmacology 33: 275-317 (1994)
Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| PubMed
| 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 265: 1272-9 (1993)
BindingDB Entry DOI: 10.7270/Q2833QJ4 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
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| 6.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 265: 1272-9 (1993)
BindingDB Entry DOI: 10.7270/Q2833QJ4 |
More data for this Ligand-Target Pair | |
Trp Aprorepressor
(Escherichia coli (strain K12)) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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| PDB PubMed
| n/a | n/a | n/a | 2.88E+4 | n/a | n/a | n/a | n/a | n/a |
University of Chicago
| Assay Description Binding assay of L-trptophan and analogues to trp aporepressor |
J Biol Chem 262: 4922-7 (1987)
BindingDB Entry DOI: 10.7270/Q25T3J3J |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 139 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |
Norepinephrine Monoamine transporters
(Rattus norvegicus) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | Reactome pathway KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50073691
(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)Show InChI InChI=1S/C11H14N2/c1-8-2-3-11-10(6-8)9(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |