BDBM50074208 3-{3-[4-(3-Phenyl-propyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole::CHEMBL352123

SMILES: C(CN1CCN(CCCc2ccccc2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key: InChIKey=VLEMMBPSWBHHED-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50074208 (3-{3-[4-(3-Phenyl-propyl)-piperazin-1-yl]-propyl}-...) Show SMILES C(CN1CCN(CCCc2ccccc2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C26H32N6/c1-2-6-22(7-3-1)8-4-12-30-14-16-31(17-15-30)13-5-9-23-19-27-26-11-10-24(18-25(23)26)32-20-28-29-21-32/h1-3,6-7,10-11,18-21,27H,4-5,8-9,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.				J Med Chem 42: 691-705 (1999) Article DOI: 10.1021/jm980569z BindingDB Entry DOI: 10.7270/Q2ZG6RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50074208 (3-{3-[4-(3-Phenyl-propyl)-piperazin-1-yl]-propyl}-...) Show SMILES C(CN1CCN(CCCc2ccccc2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C26H32N6/c1-2-6-22(7-3-1)8-4-12-30-14-16-31(17-15-30)13-5-9-23-19-27-26-11-10-24(18-25(23)26)32-20-28-29-21-32/h1-3,6-7,10-11,18-21,27H,4-5,8-9,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.				J Med Chem 42: 691-705 (1999) Article DOI: 10.1021/jm980569z BindingDB Entry DOI: 10.7270/Q2ZG6RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50074208 (3-{3-[4-(3-Phenyl-propyl)-piperazin-1-yl]-propyl}-...) Show SMILES C(CN1CCN(CCCc2ccccc2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C26H32N6/c1-2-6-22(7-3-1)8-4-12-30-14-16-31(17-15-30)13-5-9-23-19-27-26-11-10-24(18-25(23)26)32-20-28-29-21-32/h1-3,6-7,10-11,18-21,27H,4-5,8-9,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT binding to the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cells				J Med Chem 42: 691-705 (1999) Article DOI: 10.1021/jm980569z BindingDB Entry DOI: 10.7270/Q2ZG6RDW
					More data for this Ligand-Target Pair