BDBM50074344 1-{3-Bromo-4-[(4-diethylamino-6-methyl-[1,3,5]triazin-2-yl)-ethyl-amino]-phenyl}-ethanone::CHEMBL167853

SMILES: CCN(CC)c1nc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)=O

InChI Key: InChIKey=OISWGVNYEQWWLK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074344 (1-{3-Bromo-4-[(4-diethylamino-6-methyl-[1,3,5]tria...) Show SMILES CCN(CC)c1nc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)=O Show InChI InChI=1S/C18H24BrN5O/c1-6-23(7-2)17-20-13(5)21-18(22-17)24(8-3)16-10-9-14(12(4)25)11-15(16)19/h9-11H,6-8H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair