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SMILES: CCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)S(C)(=O)=O

InChI Key: InChIKey=MEFQGRNJRJHFMP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074345   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50074345
PNG
(CHEMBL167171 | N*2*-(2-Bromo-4-methanesulfonyl-phe...)
Show SMILES CCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)S(C)(=O)=O
Show InChI InChI=1S/C18H25BrN4O2S/c1-6-22(7-2)17-11-13(4)20-18(21-17)23(8-3)16-10-9-14(12-15(16)19)26(5,24)25/h9-12H,6-8H2,1-5H3
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Article
PubMed
 24n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant corticotropin releasing factor receptor 1

J Med Chem 42: 805-18 (1999)


Article DOI: 10.1021/jm980222w
BindingDB Entry DOI: 10.7270/Q29S1Q63
More data for this
Ligand-Target Pair