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SMILES: CCN(c1nc(C)cc(n1)N(CCOC)CCOC)c1ccc(cc1Br)C(C)C

InChI Key: InChIKey=VTTGJOYJTWSWLG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074410   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50074410
PNG
(CHEMBL354859 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...)
Show SMILES CCN(c1nc(C)cc(n1)N(CCOC)CCOC)c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C22H33BrN4O2/c1-7-27(20-9-8-18(16(2)3)15-19(20)23)22-24-17(4)14-21(25-22)26(10-12-28-5)11-13-29-6/h8-9,14-16H,7,10-13H2,1-6H3
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Article
PubMed
 25n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant corticotropin releasing factor receptor 1

J Med Chem 42: 805-18 (1999)


Article DOI: 10.1021/jm980222w
BindingDB Entry DOI: 10.7270/Q29S1Q63
More data for this
Ligand-Target Pair