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SMILES: CCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C

InChI Key: InChIKey=WPFPPHFVPZRZFR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074413   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50074413
PNG
(CHEMBL169094 | N*2*-(4-Dimethylamino-2-trifluorome...)
Show SMILES CCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C
Show InChI InChI=1S/C20H28F3N5/c1-7-27(8-2)18-12-14(4)24-19(25-18)28(9-3)17-11-10-15(26(5)6)13-16(17)20(21,22)23/h10-13H,7-9H2,1-6H3
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 11n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant corticotropin releasing factor receptor 1

J Med Chem 42: 805-18 (1999)


Article DOI: 10.1021/jm980222w
BindingDB Entry DOI: 10.7270/Q29S1Q63
More data for this
Ligand-Target Pair