BDBM50074580 CHEMBL3410108

SMILES: Cn1nc(cc1-c1ccnc(NC(=O)C2CC2)c1)C(N)=O

InChI Key: InChIKey=FOPOCGTVFRHABR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50074580 (CHEMBL3410108) Show SMILES Cn1nc(cc1-c1ccnc(NC(=O)C2CC2)c1)C(N)=O Show InChI InChI=1S/C14H15N5O2/c1-19-11(7-10(18-19)13(15)20)9-4-5-16-12(6-9)17-14(21)8-2-3-8/h4-8H,2-3H2,1H3,(H2,15,20)(H,16,17,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) activity by competitive binding assay				Bioorg Med Chem Lett 25: 1856-63 (2015) Article DOI: 10.1016/j.bmcl.2015.03.046 BindingDB Entry DOI: 10.7270/Q2222WH5
					More data for this Ligand-Target Pair