BDBM50074586 CHEMBL3410102

SMILES: O=C(Nc1cc(ccn1)-c1ccc2ccccc2c1)C1CC1

InChI Key: InChIKey=TUYQTTYISMZZOL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50074586 (CHEMBL3410102) Show SMILES O=C(Nc1cc(ccn1)-c1ccc2ccccc2c1)C1CC1 Show InChI InChI=1S/C19H16N2O/c22-19(14-6-7-14)21-18-12-17(9-10-20-18)16-8-5-13-3-1-2-4-15(13)11-16/h1-5,8-12,14H,6-7H2,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) activity by competitive binding assay				Bioorg Med Chem Lett 25: 1856-63 (2015) Article DOI: 10.1016/j.bmcl.2015.03.046 BindingDB Entry DOI: 10.7270/Q2222WH5
					More data for this Ligand-Target Pair