BDBM50074701 CHEMBL3410155

SMILES: NC(=O)[C@H]([C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2NC1=O)c1ncon1

InChI Key: InChIKey=DVPMRDQLGGNJPW-LDBYXDLTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50074701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Notch 1 intracellular domain (Notch 1) (Homo sapiens (Human))	BDBM50074701 (CHEMBL3410155) Show SMILES NC(=O)[C@H]([C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2NC1=O)c1ncon1 |r,t:15| Show InChI InChI=1S/C24H21F3N6O4/c25-24(26,27)11-10-15(17(19(28)34)20-29-12-37-33-20)22(35)32-21-23(36)30-16-9-5-4-8-14(16)18(31-21)13-6-2-1-3-7-13/h1-9,12,15,17,21H,10-11H2,(H2,28,34)(H,30,36)(H,32,35)/t15-,17+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Notch 3 intracellular domain (Notch 3) (Homo sapiens (Human))	BDBM50074701 (CHEMBL3410155) Show SMILES NC(=O)[C@H]([C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2NC1=O)c1ncon1 |r,t:15| Show InChI InChI=1S/C24H21F3N6O4/c25-24(26,27)11-10-15(17(19(28)34)20-29-12-37-33-20)22(35)32-21-23(36)30-16-9-5-4-8-14(16)18(31-21)13-6-2-1-3-7-13/h1-9,12,15,17,21H,10-11H2,(H2,28,34)(H,30,36)(H,32,35)/t15-,17+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	656	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair