BDBM50074747 3-(3-Chloro-phenyl)-1H-quinolin-4-one::CHEMBL7801

SMILES: Oc1c(cnc2ccccc12)-c1cccc(Cl)c1

InChI Key: InChIKey=UIHKBJZDQJFFDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50074747 (3-(3-Chloro-phenyl)-1H-quinolin-4-one | CHEMBL7801) Show SMILES Oc1c(cnc2ccccc12)-c1cccc(Cl)c1 Show InChI InChI=1S/C15H10ClNO/c16-11-5-3-4-10(8-11)13-9-17-14-7-2-1-6-12(14)15(13)18/h1-9H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor-dependent phosphorylation				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
					More data for this Ligand-Target Pair