BDBM50074961 2-p-Tolyl-4,5-dihydro-oxazole-4-carboxylic acid hydroxyamide::CHEMBL321062

SMILES: Cc1ccc(cc1)C1=NC(CO1)C(=O)NO

InChI Key: InChIKey=ALXPNNJIODXGCI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50074961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UDP-3-O-acyl-GlcNAc deacetylase (LpxC) (Pseudomonas aeruginosa)	BDBM50074961 (2-p-Tolyl-4,5-dihydro-oxazole-4-carboxylic acid hy...) Show SMILES Cc1ccc(cc1)C1=NC(CO1)C(=O)NO |t:8| Show InChI InChI=1S/C11H12N2O3/c1-7-2-4-8(5-3-7)11-12-9(6-16-11)10(14)13-15/h2-5,9,15H,6H2,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of P. aeruginosa UDP-3-O-acyl-N-acetylglucosamine Deacetylase (LpxC) in vitro.				J Med Chem 45: 3112-29 (2002) BindingDB Entry DOI: 10.7270/Q2N58KP8
					More data for this Ligand-Target Pair
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LxpC) (Escherichia coli)	BDBM50074961 (2-p-Tolyl-4,5-dihydro-oxazole-4-carboxylic acid hy...) Show SMILES Cc1ccc(cc1)C1=NC(CO1)C(=O)NO |t:8| Show InChI InChI=1S/C11H12N2O3/c1-7-2-4-8(5-3-7)11-12-9(6-16-11)10(14)13-15/h2-5,9,15H,6H2,1H3,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of UDP-3-O-[R-3-hydroxymyristoyl]-GlcNAc deacetylase using coupled radiochemical assay (WAVE) in E. coli strain JB 1104				Bioorg Med Chem Lett 9: 313-8 (1999) BindingDB Entry DOI: 10.7270/Q2CJ8CNN
					More data for this Ligand-Target Pair