BDBM50075130 1-[(S)-3-(Pyrrolidine-1-carbonyl)-3,4-dihydro-1H-isoquinolin-2-yl]-heptane-1,6-dione::CHEMBL423002

SMILES: CC(=O)CCCCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1CCCC1

InChI Key: InChIKey=RIPRIMPWYZQYKB-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50075130 (1-[(S)-3-(Pyrrolidine-1-carbonyl)-3,4-dihydro-1H-i...) Show SMILES CC(=O)CCCCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C21H28N2O3/c1-16(24)8-2-5-11-20(25)23-15-18-10-4-3-9-17(18)14-19(23)21(26)22-12-6-7-13-22/h3-4,9-10,19H,2,5-8,11-15H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lille II Curated by ChEMBL					Assay Description Inhibition of Prolyl endopeptidase				Bioorg Med Chem Lett 9: 437-42 (1999) BindingDB Entry DOI: 10.7270/Q2348JJR
					More data for this Ligand-Target Pair