BDBM50075279 (2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-2-[3-(3,4-dichloro-benzyl)-2-oxo-imidazolidin-1-yl]-3-(1H-indol-3-yl)-butyramide::CHEMBL147092
SMILES: C[C@H]([C@@H](N1CCN(Cc2ccc(Cl)c(Cl)c2)C1=O)C(=O)NC[C@H]1OC[C@H](N)CO1)c1c[nH]c2ccccc12
InChI Key: InChIKey=ZQKHTXVTPWRZTN-JHTIXPBXSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50075279![]() ((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-2-[3-(3...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity was evaluated against human Somatostatin receptor type 2 (hSSTR-2) | Bioorg Med Chem Lett 9: 491-6 (1999) BindingDB Entry DOI: 10.7270/Q2FB5235 | |||||||||||
More data for this Ligand-Target Pair |