BDBM50075756 4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)-1H-pyrrol-2-yl)pyridine::4-[3-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL155687::CHEMBL2435136

SMILES: CS(=O)c1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1

InChI Key: InChIKey=MHSKRZAFVKHGJT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50075756 (4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...) Show SMILES CS(=O)c1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H17FN2OS/c1-27(26)19-8-4-16(5-9-19)21-14-20(15-2-6-18(23)7-3-15)22(25-21)17-10-12-24-13-11-17/h2-14,25H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against p38-alpha kinase				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075756 (4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...) Show SMILES CS(=O)c1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H17FN2OS/c1-27(26)19-8-4-16(5-9-19)21-14-20(15-2-6-18(23)7-3-15)22(25-21)17-10-12-24-13-11-17/h2-14,25H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	671	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glucagon receptor				Citation and Details Article DOI: 10.1007/s00044-013-0801-3 BindingDB Entry DOI: 10.7270/Q20G3MM3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50075756 (4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...) Show SMILES CS(=O)c1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H17FN2OS/c1-27(26)19-8-4-16(5-9-19)21-14-20(15-2-6-18(23)7-3-15)22(25-21)17-10-12-24-13-11-17/h2-14,25H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Islamic University of Gaza Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin)				J Med Chem 52: 2613-7 (2009) Article DOI: 10.1021/jm801467h BindingDB Entry DOI: 10.7270/Q21Z449S
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075756 (4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...) Show SMILES CS(=O)c1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H17FN2OS/c1-27(26)19-8-4-16(5-9-19)21-14-20(15-2-6-18(23)7-3-15)22(25-21)17-10-12-24-13-11-17/h2-14,25H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair