BDBM50075760 4-[5-(4-Chloro-phenyl)-3-(3-methoxy-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL158477

SMILES: COc1cccc(c1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=RFNVDMKXJPQRBI-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50075760 (4-[5-(4-Chloro-phenyl)-3-(3-methoxy-phenyl)-1H-pyr...) Show SMILES COc1cccc(c1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O/c1-26-19-4-2-3-17(13-19)20-14-21(15-5-7-18(23)8-6-15)25-22(20)16-9-11-24-12-10-16/h2-14,25H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against p38-alpha kinase				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075760 (4-[5-(4-Chloro-phenyl)-3-(3-methoxy-phenyl)-1H-pyr...) Show SMILES COc1cccc(c1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O/c1-26-19-4-2-3-17(13-19)20-14-21(15-5-7-18(23)8-6-15)25-22(20)16-9-11-24-12-10-16/h2-14,25H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	421	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glucagon receptor				Citation and Details Article DOI: 10.1007/s00044-013-0801-3 BindingDB Entry DOI: 10.7270/Q20G3MM3
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075760 (4-[5-(4-Chloro-phenyl)-3-(3-methoxy-phenyl)-1H-pyr...) Show SMILES COc1cccc(c1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O/c1-26-19-4-2-3-17(13-19)20-14-21(15-5-7-18(23)8-6-15)25-22(20)16-9-11-24-12-10-16/h2-14,25H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075760 (4-[5-(4-Chloro-phenyl)-3-(3-methoxy-phenyl)-1H-pyr...) Show SMILES COc1cccc(c1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O/c1-26-19-4-2-3-17(13-19)20-14-21(15-5-7-18(23)8-6-15)25-22(20)16-9-11-24-12-10-16/h2-14,25H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair