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SMILES: CCCOc1cccc(OCCC)c1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=RYGNZEQECYUPSL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Mus musculus)	BDBM50075763 (4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...) Show SMILES CCCOc1cccc(OCCC)c1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 |(9.36,4.01,;8.87,2.56,;7.36,2.26,;6.87,.79,;5.46,.18,;4.21,1.09,;2.81,.46,;2.64,-1.08,;3.88,-1.98,;3.72,-3.51,;2.32,-4.14,;1.07,-3.23,;-.34,-3.85,;5.28,-1.36,;6.53,-2.27,;7.99,-1.8,;8.9,-3.04,;7.99,-4.29,;6.52,-3.81,;5.27,-4.7,;3.93,-3.93,;2.6,-4.7,;2.6,-6.24,;3.95,-7.01,;5.27,-6.24,;10.43,-3.06,;11.18,-4.39,;12.72,-4.39,;13.51,-3.06,;15.05,-3.06,;12.74,-1.73,;11.2,-1.73,)| Show InChI InChI=1S/C27H27ClN2O2/c1-3-16-31-24-6-5-7-25(32-17-4-2)26(24)22-18-23(19-8-10-21(28)11-9-19)30-27(22)20-12-14-29-15-13-20/h5-15,18,30H,3-4,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of 125 I-glucagon to the murine glucagon receptor (mGLUR) expressed on ...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075763 (4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...) Show SMILES CCCOc1cccc(OCCC)c1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 |(9.36,4.01,;8.87,2.56,;7.36,2.26,;6.87,.79,;5.46,.18,;4.21,1.09,;2.81,.46,;2.64,-1.08,;3.88,-1.98,;3.72,-3.51,;2.32,-4.14,;1.07,-3.23,;-.34,-3.85,;5.28,-1.36,;6.53,-2.27,;7.99,-1.8,;8.9,-3.04,;7.99,-4.29,;6.52,-3.81,;5.27,-4.7,;3.93,-3.93,;2.6,-4.7,;2.6,-6.24,;3.95,-7.01,;5.27,-6.24,;10.43,-3.06,;11.18,-4.39,;12.72,-4.39,;13.51,-3.06,;15.05,-3.06,;12.74,-1.73,;11.2,-1.73,)| Show InChI InChI=1S/C27H27ClN2O2/c1-3-16-31-24-6-5-7-25(32-17-4-2)26(24)22-18-23(19-8-10-21(28)11-9-19)30-27(22)20-12-14-29-15-13-20/h5-15,18,30H,3-4,16-17H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075763 (4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...) Show SMILES CCCOc1cccc(OCCC)c1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 |(9.36,4.01,;8.87,2.56,;7.36,2.26,;6.87,.79,;5.46,.18,;4.21,1.09,;2.81,.46,;2.64,-1.08,;3.88,-1.98,;3.72,-3.51,;2.32,-4.14,;1.07,-3.23,;-.34,-3.85,;5.28,-1.36,;6.53,-2.27,;7.99,-1.8,;8.9,-3.04,;7.99,-4.29,;6.52,-3.81,;5.27,-4.7,;3.93,-3.93,;2.6,-4.7,;2.6,-6.24,;3.95,-7.01,;5.27,-6.24,;10.43,-3.06,;11.18,-4.39,;12.72,-4.39,;13.51,-3.06,;15.05,-3.06,;12.74,-1.73,;11.2,-1.73,)| Show InChI InChI=1S/C27H27ClN2O2/c1-3-16-31-24-6-5-7-25(32-17-4-2)26(24)22-18-23(19-8-10-21(28)11-9-19)30-27(22)20-12-14-29-15-13-20/h5-15,18,30H,3-4,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075763 (4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...) Show SMILES CCCOc1cccc(OCCC)c1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 |(9.36,4.01,;8.87,2.56,;7.36,2.26,;6.87,.79,;5.46,.18,;4.21,1.09,;2.81,.46,;2.64,-1.08,;3.88,-1.98,;3.72,-3.51,;2.32,-4.14,;1.07,-3.23,;-.34,-3.85,;5.28,-1.36,;6.53,-2.27,;7.99,-1.8,;8.9,-3.04,;7.99,-4.29,;6.52,-3.81,;5.27,-4.7,;3.93,-3.93,;2.6,-4.7,;2.6,-6.24,;3.95,-7.01,;5.27,-6.24,;10.43,-3.06,;11.18,-4.39,;12.72,-4.39,;13.51,-3.06,;15.05,-3.06,;12.74,-1.73,;11.2,-1.73,)| Show InChI InChI=1S/C27H27ClN2O2/c1-3-16-31-24-6-5-7-25(32-17-4-2)26(24)22-18-23(19-8-10-21(28)11-9-19)30-27(22)20-12-14-29-15-13-20/h5-15,18,30H,3-4,16-17H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair