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SMILES: Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)C1CCCCC1

InChI Key: InChIKey=KVOWJSITTRQRSW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50075769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Mus musculus)	BDBM50075769 (4-[5-Cyclohexyl-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)C1CCCCC1 Show InChI InChI=1S/C21H21FN2/c22-18-8-6-15(7-9-18)19-14-20(16-4-2-1-3-5-16)24-21(19)17-10-12-23-13-11-17/h6-14,16,24H,1-5H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of 125 I-glucagon to the murine glucagon receptor (mGLUR) expressed on ...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075769 (4-[5-Cyclohexyl-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)C1CCCCC1 Show InChI InChI=1S/C21H21FN2/c22-18-8-6-15(7-9-18)19-14-20(16-4-2-1-3-5-16)24-21(19)17-10-12-23-13-11-17/h6-14,16,24H,1-5H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075769 (4-[5-Cyclohexyl-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)C1CCCCC1 Show InChI InChI=1S/C21H21FN2/c22-18-8-6-15(7-9-18)19-14-20(16-4-2-1-3-5-16)24-21(19)17-10-12-23-13-11-17/h6-14,16,24H,1-5H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glucagon receptor				Citation and Details Article DOI: 10.1007/s00044-013-0801-3 BindingDB Entry DOI: 10.7270/Q20G3MM3
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075769 (4-[5-Cyclohexyl-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)C1CCCCC1 Show InChI InChI=1S/C21H21FN2/c22-18-8-6-15(7-9-18)19-14-20(16-4-2-1-3-5-16)24-21(19)17-10-12-23-13-11-17/h6-14,16,24H,1-5H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075769 (4-[5-Cyclohexyl-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)C1CCCCC1 Show InChI InChI=1S/C21H21FN2/c22-18-8-6-15(7-9-18)19-14-20(16-4-2-1-3-5-16)24-21(19)17-10-12-23-13-11-17/h6-14,16,24H,1-5H2	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50075769 (4-[5-Cyclohexyl-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)C1CCCCC1 Show InChI InChI=1S/C21H21FN2/c22-18-8-6-15(7-9-18)19-14-20(16-4-2-1-3-5-16)24-21(19)17-10-12-23-13-11-17/h6-14,16,24H,1-5H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against p38-alpha kinase				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair