BDBM50075956 CHEMBL3415789
SMILES: OC(=O)C([O-])=O.C[NH+](CC#C)CC(=C)Cc1ccc(F)c(F)c1
InChI Key: InChIKey=IMQOHHJKSAHJQM-UHFFFAOYSA-O
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50075956![]() (CHEMBL3415789) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in Sf9 cells using 5-phenylacetaldehyde substrate assessed as hydrogen peroxide production after 1 hr... | J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50075956![]() (CHEMBL3415789) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ... | J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat)) | BDBM50075956![]() (CHEMBL3415789) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL | Assay Description Inhibition of rat brain MAO-B in nuclei-free homogenates using [14C]phenylacetaldehyde substrate after 20 mins by liquid scintillation counting | J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Rattus norvegicus (rat)) | BDBM50075956![]() (CHEMBL3415789) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL | Assay Description Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation counting | J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3 | |||||||||||
More data for this Ligand-Target Pair |