BDBM50076208 CHEMBL3416055

SMILES: Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCF

InChI Key: InChIKey=JTPWNGVIUSRWDW-SCZZXKLOSA-N

Data: 1 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50076208 (CHEMBL3416055) Show SMILES Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCF |r| Show InChI InChI=1S/C12H15ClFNO/c13-9-1-2-12(16-4-3-14)11(6-9)10-5-8(10)7-15/h1-2,6,8,10H,3-5,7,15H2/t8-,10+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	632	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50076208 (CHEMBL3416055) Show SMILES Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCF |r| Show InChI InChI=1S/C12H15ClFNO/c13-9-1-2-12(16-4-3-14)11(6-9)10-5-8(10)7-15/h1-2,6,8,10H,3-5,7,15H2/t8-,10+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50076208 (CHEMBL3416055) Show SMILES Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCF |r| Show InChI InChI=1S/C12H15ClFNO/c13-9-1-2-12(16-4-3-14)11(6-9)10-5-8(10)7-15/h1-2,6,8,10H,3-5,7,15H2/t8-,10+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in CHO cells by patch clamp method				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50076208 (CHEMBL3416055) Show SMILES Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCF |r| Show InChI InChI=1S/C12H15ClFNO/c13-9-1-2-12(16-4-3-14)11(6-9)10-5-8(10)7-15/h1-2,6,8,10H,3-5,7,15H2/t8-,10+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair