BDBM50076209 CHEMBL3416056

SMILES: Cl.NC[C@@H]1C[C@H]1c1cc(Cl)ccc1OCC(F)F

InChI Key: InChIKey=LKSLPKUFIJEDDA-IONNQARKSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50076209 (CHEMBL3416056) Show SMILES Cl.NC[C@@H]1C[C@H]1c1cc(Cl)ccc1OCC(F)F |r| Show InChI InChI=1S/C12H14ClF2NO/c13-8-1-2-11(17-6-12(14)15)10(4-8)9-3-7(9)5-16/h1-2,4,7,9,12H,3,5-6,16H2/t7-,9+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50076209 (CHEMBL3416056) Show SMILES Cl.NC[C@@H]1C[C@H]1c1cc(Cl)ccc1OCC(F)F |r| Show InChI InChI=1S/C12H14ClF2NO/c13-8-1-2-11(17-6-12(14)15)10(4-8)9-3-7(9)5-16/h1-2,4,7,9,12H,3,5-6,16H2/t7-,9+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50076209 (CHEMBL3416056) Show SMILES Cl.NC[C@@H]1C[C@H]1c1cc(Cl)ccc1OCC(F)F |r| Show InChI InChI=1S/C12H14ClF2NO/c13-8-1-2-11(17-6-12(14)15)10(4-8)9-3-7(9)5-16/h1-2,4,7,9,12H,3,5-6,16H2/t7-,9+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	914	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair