BDBM50076212 CHEMBL3416059

SMILES: Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCCF

InChI Key: InChIKey=BYYLWJMIZLRGBJ-KOLCDFICSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50076212 (CHEMBL3416059) Show SMILES Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCCF |r| Show InChI InChI=1S/C13H17ClFNO/c14-10-2-3-13(17-5-1-4-15)12(7-10)11-6-9(11)8-16/h2-3,7,9,11H,1,4-6,8,16H2/t9-,11+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	206	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50076212 (CHEMBL3416059) Show SMILES Cl.NC[C@H]1C[C@@H]1c1cc(Cl)ccc1OCCCF |r| Show InChI InChI=1S/C13H17ClFNO/c14-10-2-3-13(17-5-1-4-15)12(7-10)11-6-9(11)8-16/h2-3,7,9,11H,1,4-6,8,16H2/t9-,11+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.91E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 58: 1992-2002 (2015) Article DOI: 10.1021/jm5019274 BindingDB Entry DOI: 10.7270/Q2BC4181
					More data for this Ligand-Target Pair