BDBM50076412 4-(4-Methyl-piperazin-1-yl)-5,6-dihydro-benzo[f]isoquinoline::CHEMBL288497

SMILES: CN1CCN(CC1)c1nccc-2c1CCc1ccccc-21

InChI Key: InChIKey=QBPBAVLPSVMXHP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50076412 (4-(4-Methyl-piperazin-1-yl)-5,6-dihydro-benzo[f]is...) Show SMILES CN1CCN(CC1)c1nccc-2c1CCc1ccccc-21 Show InChI InChI=1S/C18H21N3/c1-20-10-12-21(13-11-20)18-17-7-6-14-4-2-3-5-15(14)16(17)8-9-19-18/h2-5,8-9H,6-7,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair