BDBM50076417 6-(4-Methyl-piperazin-1-yl)-7,8,8a,9,10,11,12,12a-octahydro-benzo[k]phenanthridine::CHEMBL43187

SMILES: CN1CCN(CC1)c1nc2ccccc2c2C3CCCCC3CCc12

InChI Key: InChIKey=AFZCODAIYOWGDR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50076417 (6-(4-Methyl-piperazin-1-yl)-7,8,8a,9,10,11,12,12a-...) Show SMILES CN1CCN(CC1)c1nc2ccccc2c2C3CCCCC3CCc12 Show InChI InChI=1S/C22H29N3/c1-24-12-14-25(15-13-24)22-19-11-10-16-6-2-3-7-17(16)21(19)18-8-4-5-9-20(18)23-22/h4-5,8-9,16-17H,2-3,6-7,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membrane				J Med Chem 42: 1556-75 (1999) Article DOI: 10.1021/jm981112s BindingDB Entry DOI: 10.7270/Q2D50NPW
					More data for this Ligand-Target Pair