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SMILES: CN1CCN(CC1)c1nc2ccccc2c(c1COC1CCCO1)-c1ccccc1

InChI Key: InChIKey=QCGLXCFFWQYKLF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076418   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 3A/3B


(Rattus norvegicus-RAT)		BDBM50076418
PNG
(2-(4-Methyl-piperazin-1-yl)-4-phenyl-3-(tetrahydro...)
Show SMILES CN1CCN(CC1)c1nc2ccccc2c(c1COC1CCCO1)-c1ccccc1
Show InChI InChI=1S/C25H29N3O2/c1-27-13-15-28(16-14-27)25-21(18-30-23-12-7-17-29-23)24(19-8-3-2-4-9-19)20-10-5-6-11-22(20)26-25/h2-6,8-11,23H,7,12-18H2,1H3
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UniChem

Similars
Article
PubMed
 3.60n/an/an/an/an/an/an/an/a



Universit£ di Siena

Curated by ChEMBL


Assay Description
Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue

J Med Chem 42: 1556-75 (1999)


Article DOI: 10.1021/jm981112s
BindingDB Entry DOI: 10.7270/Q2D50NPW
More data for this
Ligand-Target Pair