BDBM50076702 (R)-8-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one::CHEMBL268569

SMILES: CCC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F

InChI Key: InChIKey=XMLSUKKPQHFSIY-SNVBAGLBSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50076702 ((R)-8-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...) Show SMILES CCC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O/c1-2-3-10-5-4-9-6-11-12(16(17,18)19)7-15(22)21-14(11)8-13(9)20-10/h6-8,10,20H,2-5H2,1H3,(H,21,22)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assay				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50076702 ((R)-8-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...) Show SMILES CCC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O/c1-2-3-10-5-4-9-6-11-12(16(17,18)19)7-15(22)21-14(11)8-13(9)20-10/h6-8,10,20H,2-5H2,1H3,(H,21,22)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50076702 ((R)-8-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...) Show SMILES CCC[C@@H]1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F Show InChI InChI=1S/C16H17F3N2O/c1-2-3-10-5-4-9-6-11-12(16(17,18)19)7-15(22)21-14(11)8-13(9)20-10/h6-8,10,20H,2-5H2,1H3,(H,21,22)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell lines				Bioorg Med Chem Lett 9: 1009-12 (1999) BindingDB Entry DOI: 10.7270/Q2F18XWV
					More data for this Ligand-Target Pair